The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants tacrolimus (FK506) and sirolimus … Ver mais FK506 binding protein 5, also known as FKBP5, is a protein which in humans is encoded by the FKBP5 gene. Ver mais The FKBP5 gene has been found to have multiple polyadenylation sites and is statistically associated with a higher rate of depressive disorders. Decreased … Ver mais FKBP5 has been shown to interact with Heat shock protein 90kDa alpha (cytosolic), member A1. Ver mais • Schiene-Fischer C, Yu C (April 2001). "Receptor accessory folding helper enzymes: the functional role of peptidyl prolyl cis/trans isomerases". FEBS Letters. 495 (1–2): 1–6. Ver mais As a key player in several diseases like stress-related disorders, chronic pain, and obesity, FKBP51 is an attractive drug target. SAFit2 currently the most best characterized FKBP51 ligand, has shown promising effects in numerous animal models. Macrocyclic … Ver mais • FKBP4 - a functional antagonist to FKBP5 at corticoid receptors • FKBP3 - a DNA binding FKBP Ver mais WebChromosome Chromosomes are the genetic material present in all cells. They are present in the nucleus of a eukaryotic cell. They are a thread-like structure. Each chromosome of a eukaryotic cell contains DNA and associated proteins, known as histone proteins.
Is FKBP5 a genetic marker of affective psychosis? A case control …
Web2 de nov. de 2006 · FKBP5, synonymous to FKBP51 and FKBP54, is located on chromosome 6p21, a chromosomal region associated with bipolar disorder and … WebThe FKBP5 intracellular concentration affects the binding affinity of the glucocorticoid receptor (GR) to glucocorticoids (GCs). This gene has glucocorticoid response elements … hierarchical recurrent neural network
Fkbp5 FK506 binding protein 5 [ Mus musculus (house mouse) ]
Web15 de ago. de 2024 · Chromosome Abnormalities Fact Sheet. Chromosome abnormalities can be numerical or structural. A numerical abnormality mean an individual is either missing one of the chromosomes from a pair or has more than two chromosomes instead of a pair. A structural abnormality means the chromosome's structure has been … Web13 de ago. de 2015 · The FKBP5 gene is located on the short arm of chromosome 6 (6p21.31), spans around 155 kb, and consists of 13 exons ( Figure 3 ). FKBP5 … Web1 de jan. de 2024 · On the other hand, the FKBP51 is a 51 kDa protein encoded by FKBP5 gene, which is located on the short arm of chromosome 6 (chromosome 6p21.31) and spans around 155 kb (Mahon et al., 2013). how far does wifi signal reach